N, ndimethylformamide is commonly used as a solvent. Page 1 of 10 material safety data sheet methanol product name methanol ch 3oh synonyms alcohol, methyl hydroxide, methyl hydrate, wood alcohol, wood spirit product use. Application n,n dimethylformamide was used to solubilize mtt crystals in cell viability assays. Vithane resins in dimethylformamide dmf are a family of polyurethane elastomers manufactured and marketed by rohm and haas company, a wholly owned subsidiary of the dow chemical company, and its affiliated companies. It has a role as a polar aprotic solvent and a hepatotoxic agent. Canadian association of chemical distributors safety data. The solvent properties of dmf are particularly attractive because of the high dielectric constant, the aprotic nature of the solvent, its wide liquid range and low volatility. Acetylene, dissolved in dmf 100 74862 ingredient name % cas number there are no additional ingredients present which, within the current knowledge of the supplier and in the. Sodium hydroxide safety data sheet according to federal register vol. According to the information received during the public consultation from industry stakeholders of the chemical, pharmaceutical and textiles sectors 6 rcom, 2012, as well as from the gas sector association rcom, 2014, research for alternative solvents andor. Dmf is miscible with water in all proportions and is a powerful solvent for a variety of organic, inorganic, and resin products. Hhhhh dmf is prepared by combining methyl formate and dimethylamine or by reaction of dimethylamine with carbon monoxide.
Its health effects include hepatotoxicity and male reproductoxicity, possibly linked with mitochondrial dna mtdna alterations. Canadian association of chemical distributors safety data sheet 1. Acgih threshold limit values 2011 rel 10 ppm 30 mgm3 us. Safety data sheet n,ndimethylformamide bdh 1117 vwr. Chemical information document 2 sourcing compliant formulations from your chemical suppliers communicate with the responsible person for chemical management at upstream suppliers to ensure formulations meet brand requirements. Chemical information document for dimethylformamide dmf. Chemical information document 2 sourcing compliant formulations from your chemical suppliers communicate with the responsible person for chemical management at upstream. Elastomers are resilient polymers that can bend or stretch and then return to their original shape. Identification product name n,n dimethylformamide d7 casno 4472417 synonyms no information available recommended use laboratory chemicals.
If there is significant potential for skin contact, monitoring should be done to measure the level of dmf metabolites in urine specimans at the end of the shift. The cas number is the substance numerical identifier assigned by the chemical abstracts service, a division of the american chemical society, to substances registered in the cas. Dmf is one of a class of solvents designated as polar aprotics. Use water spray, alcoholresistant foam, dry chemical or carbon dioxide.
N, n dimethylformamide dmf is a solvent with a low evaporation rate, useful for preparing solutions with a variety of hydrophobic organic compounds used in molecular biology applications. Material safety data sheet section 1 n,ndimethylformamide 1 chemical product and company identification msds name. View or download the n,ndimethylformamide msds material safety data sheet or sds for 103034 from merck. Page 1 of 9 msds dimethylformamide material safety data sheet msds dimethylformamide 1.
Dec 01, 2019 dmf is used in the production of acrylic fibers and plastics. According to the information received during the public consultation from industry stakeholders of the chemical. Material safety data sheet methanol product name methanol ch 3oh synonyms alcohol, methyl hydroxide, methyl hydrate, wood alcohol, wood spirit product use solvent, fuel, feedstock company identification methanol holdings trinidad limited atlantic avenue, point lisas industrial estate point lisas, trinidad, west indies. The user must determine suitability of this information for his application. Dimethylformamide solvent for peptide coupling, used as a wash after each deprotection and coupling step in tboc, used as a solvent in fmoc, solvent with low evaporation rate, catalyst in synthesis of acid halides. Cdc niosh publications and products preventing adverse. Commonly abbreviated as dmf although this initialism is sometimes used for dimethylfuran, or dimethyl. Acetylene, dissolved in dmf 100 74862 ingredient name % cas number there are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section. Safety data sheet creation date 12jan2015 revision date 19jan2018 revision number 4 1. Dimethylformamide dmf is a colorless, watersoluble liquid with a faint ammonialike odor. Dimethyl sulfoxide page 2 of 5 cause liver and kidney damage. Safety data sheet northwest missouri state university. This organic solvent is used in acrylic fiber spinning, chemical manufacturing, and pharmaceutical production.
It is a precursor for numerous reactions such as formylation. Commonly abbreviated as dmf although this initialism is sometimes used for dimethylfuran, or dimethyl fumarate, this colourless liquid is miscible with water and the majority of organic liquids. Check regularly the formulation and sds from your chemical supplier to ensure dmf is not being added. N,n dimethylformamide included in the candidate list of substances of very high concern svhc. This high solubility of inorganic substances also leads to the application of dmf in the production of high voltage capacitors. As for most amidesthe spectroscopic evidence indicates partial. Toxicity data skin rabbit 4,720 mgkg ld50 oral rat 2,800 mgkg ld50 6 hr. The information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. It is a volatile organic compound and a member of formamides.
Panjiva uses over 30 international data sources to help you find qualified vendors of chemical dmf. Dimethylformamide dmf is a clear, colorless, watersoluble liquid that is used primarily as a dipolar aprotic solvent. Material safety data sheet methanol southern chemical. In case of skin contact wash off with soap and plenty of water. N,n dimethylformamide is a member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups.
Osha table z1 limits for air contaminants 29 cfr 1910. It is used for separating and refining crude from olefin gas. Hconch32 material safety data sheet n,ndimethylformamide msds. Its appearance should serve as a warning that control of exposure to dmf has. Dimethylformamide is an organic compound with the formula ch 3 2 ncoh. N,ndimethylformamide is considered to be a potent liver toxin. Chemical dmf manufacturers suppliers of chemical dmf. Inventory of existing chemical substances produced or imported in china. A new method for the preparation of secondary and tertiary p alkylaminobenzaldehyde. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Workers may be harmed from exposure to dimethylformamide. If there is significant potential for skin contact, monitoring should be done to measure the level of dmf metabolites in urine specimans at the end of the. For other components in the kit, please refer to individual material safety data sheet. N, ndimethylformamide dmf is a clear liquid that has been widely used in industries as a solvent, an additive, or an intermediate because of its extensive miscibility with water and most common organic solvents.
Dmf is used in the production of acrylic fibers and plastics. Dimetyylformamide wikipedia, the free encyclopedia. This chemical is one of the components of the antibody array assay kit. Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Chemical used in synthesis andor formulation of industrial products.
Dimethylformamide dmf is a clear, colorless, hygroscopic liquid with a slight amine odor. Avoid contact with dimethyl sulfoxide dmso solutions containing toxic materials or materials with unknown toxicological properties. Dmf is a polar hydrophilic aprotic solvent with a high boiling point. Thf material safety data sheet msds tetrahydrofuran 1. The solvent properties of dmf are particularly attractive because of the high dielectric constant, the. General description n,ndimethylformamide dmf is a polar organic solvent with a wide range of industrial applications. Material safety data sheet n,n dimethylformamide msds section 1. Product identification name dimethylformamide synonyms n,ndimethylformamide, nformyldimethylamine, dmf. It can harm the eyes, skin, lungs, liver, and heart. None information in this msds is from available published sources and is believed to be accurate. It acts as a catalyst in the synthesis of acyl chlorides.
Show this safety data sheet to the doctor in attendance. Use carbon dioxide, dry chemical or foam for extinction. Dimethylformamide dmf chemical economics handbook ceh. If inhaled if breathed in, move person into fresh air. Aug 15, 2019 dimetyylformamide wikipedia, the free encyclopedia. Pocket guide to chemical hazards 2010 pel 10 ppm 30 mgm3 us. Substancepreparation and company identification material.
Us epa guidelines for the classification determination are listed in 40 cfr. Dimethylformamide please ensure that this sds is given to, and explained to people using this product. Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. As for most amidesthe spectroscopic evidence indicates partial double bond character for the cn and co bonds. It is used as a reagent in bouveault aldehyde synthesis and also in vilsmeierhaack reaction. Identification of the substancemixture and of the companyundertaking product name.
N,ndimethylformamide included in the candidate list of substances of very. Chemical identity type exposure limit values source dimethylformamide twa 10 ppm us. Dow expects you to follow the precautions identified in this document unless your use conditions would necessitate other appropriate methods or actions. Uses advised against food, drug, pesticide or biocidal product use. It is frequently used for chemical reactions and other applications, which. Nmr solvents deuterated solvents for nmr nmr solvents nmr reference standards nmr tubes. Dmf along with methylene chloride acts as a remover of varnish or lacquers. Warn or evacuate occupants in surrou nding and downwind areas if required due to toxicity or. Dmf is also used as carrier for inks and dyes in various printing and fiberdying applications. The cas number is the substance numerical identifier assigned by the chemical abstracts service, a division of the american chemical society, to substances registered in the cas registry database. Identification product name n,ndimethylformamided7 casno 4472417 synonyms no. Msds dimethylformamide page 1 of 9 material safety data sheet.
N, ndimethylformamide dmf is a clear liquid that has been widely used in industries as a solvent, an additive, or an intermediate because of its extensive miscibility with water and most. Its appearance should serve as a warning that control of exposure to dmf has been inadequate. Chemical product and company identification product name. Avoid contact with dimethyl sulfoxide dmso solutions containing toxic materials or materials. No warranty, express or implied, is made and labchem inc.
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